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Original Articles

Clinico etiological profile of Hypoxic ischemic encephalopathy in preterms and their outcome

Year : 2016 | Volume : 4 | Issue : 1 Page : 31 - 35

Ramya C1, Shantappa K2, Srinivas Madoori3, Ravali Rao4

1Assistant Professor,3Professor,4Post graduate student, Department of Paediatrics, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar,Telangana, 2Senior Resident, Department of Paediatrics, Government Maternity Hospital, Hyderabad.

Address for correspondence: Dr.Ramya C, Assistant professor , Department of Paediatrics, Chalmeda Anand Rao Institute of Medical Sciences, Bommakal, Telangana, India

Email: drchitgope@gmail.com

Abstract

Background: Neonatal Mortality is still an issue of concern in developing countries. Perinatal asphyxia is one of the common causes of neonatal mortality. One of the important complication seen in perinatal hypoxia is Hypoxic ischemic encephalopathy (HIE).

Aims & Objectives To study the epidemiology, aetiology and early outcome of preterm newborns with birth asphyxia and admitted with HIE and their relation with the outcome of the newborn.

Material and Methods:This study was conducted at teaching cum tertiary care general hospital in rural area of Telangana between Oct 2013 to Oct 2014. Sarnat and Sarnat HIE staging, Levene Staging and Thompson Score and Neurosonogram were used in all preterm babies and it was compared with all the variables in relation to outcome.

Results: Of the total 2700 newborn, 796 were preterm and amongst them, 30 infants had HIE. Our study observed Pregnancy Induced Hypertenstion (36.6%), antepartum haemorrhage (16.6%) as risk factors. Seizures were observed in 12 newborns (40%). Out of 30 preterm infants, 16 (53.4%) recovered and 14 (46.6%) babies could not survive.

Conclusion: Male babies are more at risk of developing HIE compared to female babies. PIH, Oligohydramnios are common risk factors for causing HIE and lower the gestational age, more the chances of developing HIE and even mortality is very high

Keywords :Perinatal hypoxia, preterm infants, Hypoxic Ischemic Encephalopathy, Levene staging, Thompson score, antenatal risk factors

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