Subha Ranjan¹, Ipsita Mohapatra², G Sahoo³

^{1 2}Assistant Professor, Department of Obstetrics and Gynecology, Prathima Institute of Medical Sciences,Karimnagar,Telanagana,³Ex Professor, Department of Obstetrics and Gynecology, V.S.S medical college,Orissa.

Address for correspondence: Dr Subha Ranjan, Assistant Professor, Department of Obstetrics and Gynecology, Prathima Institute of Medical Sciences,Karimnagar,Telanagana,India

Email: drsubha2009@gmail.com

Introduction: Bacterial vaginosis (BV) is a condition characterized by a change in microbial echo system of vagina. This is a polymicrobial disorder with decrease in the number of Hydrogen peroxide (H2O2) producing lactobacillus and overgrowth of several facultative anaerobic bacteria. Treating bacterial vaginosis may prevent preterm labour and improve the perinatal outcome.The present study was done to know the association of bacterial vaginosis with preterm labour and to evaluate perinatal outcome.

Materials & Methods: A prospective case control study of 100 pregnant women (with 50 preterm and 50 term pregnancies), were evaluated for bacterial vaginosis and perinatal outcome was observed.

Results: Preterm labor (PTL) was seen in 64% of unbooked cases and majority cases (48%) were at 32-34 weeks gestational age. The test for bacterial vaginosis was positive for 24% of cases and 8% of control (P<0.05, Odds ratio=3.63,95%CI,1.08-12.18), showing its association with preterm labour. Neonatal complication was more in preterm with bacterial vaginosis.

Conclusion: From this study it is clearly evident that BV is one of the most important causes of PTL leading to various neonatal mortality, morbidity and even permanent disability. Its detection and early treatment may improve the perinatal outcome. Keywords :Bacterial vaginosis, Preterm labour, Nugent’s test, Amsel test