Sreenivas Terala¹, Ramakrishna Reddy^2, Sai Sripada Rao K³Chennamaneni Vikas⁴

¹Professor, Department of Internal Medicine ²Professor, Department of Internal Medicine,³Postgraduate student, Department of Internal Medicine, ⁴Associate Professor, Department of Radiology, Prathima Institute of Medical Sciences, Karimnagar, Andhra Pradesh, India.

Address for correspondence : Sai Sripada Rao K, Postgraduate student, Department of Internal Medicine, Prathima Institute of Medical Sciences, Karimnagar, Andhra Pradesh, India.

Email: dr.saisripadrao@gmail.com

Introduction: Takayasu arteritis (TA) is a chronic, idiopathic, inflammatory and stenotic disease of medium and large-sized arteries. The disease is more common in middle aged women. We report a 40 year female (mother) who presented with complaints of claudicating pain in both her lower limbs and upper limbs on her daily activities. On examination pulses were absent in both upper limbs and on further inquiring about her family history similar symptoms were experienced by her daughter. On further clinical examination and Radiodiagnostic technique, both females were fitting into the American College of Rheumatology criteria (ACR) for Takayasu arteritis. The etiology of TA is still unknown, but this case and review of literature indicates that there are genetic factors that play a major role in development of TA. Hence we should maintain a high index of suspicion for the possibility of TA in the siblings or other family members of affected patients.

Key words: Familial Takayasu arteritis,claudication