Jyothi K¹, Sitamahalaxmi B², Sreedevi S³

^1,2,3Assistant professor, Department of Microbiology, Kakatiya Medical College, Warangal,Telangana,India.

Address for correspondence: Dr. Jyothi. K, Assistant Professor , Department of Microbiology, Kakatiya Medical College, Warangal,Telangana,India

Email: jyothikunduru08@gmail.com

Background: Herpes simplex virus type 2 (HSV2) transmitted via sexual route is now the most common cause of genital ulcers in developed and developing countries. Increasing evidence demonstrates a substantial link between the epidemics of sexually transmitted HIV1 and HSV2 infection. HSV2 has an important role in acquiring and transmitting HIV through genital ulcers.

Aims & objective : This study was conducted to determine the seroprevalence of HSV2 in HIV seropositive individuals attending ICTC in a tertiary care hospital in Warangal and to study the sociodemographic factors influencing HSV2 seroprevalence in HIV seropositive subjects. Materials and Methods :This descriptive study was performed among 200 HIV positive patients (case group) and 200 age and sex matched non- HIV patients ( control group) attending the ICTC in a tertiary care Hospital in Warangal. For the evaluation of HSV2 infection, blood samples were obtained and assessed for IgG antibody to HSV2 using ELISA method.The data was collected and analysed.

Results :Out of 200 cases,82 were seropositive for HSV2 (41%)in case group and 24 of 200 (12%) in control group. Seropositivity was 41.4% in female and 40.6% in male, 41.8% in under and 33.3% in age over 40 years.

Conclusion : It can be derived that the seroprevalence of HSV2 in HIV positive subjects in our region is high and makes persons with HIV infection one of the most appropriate target group for serological testing of HSV2 infection.

Keywords : Herpes simplex virus (HSV2), Human Immunodeficiency Virus (HIV), seroprevalence, seropositivity.