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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="Case Series">
  <front>
    <journal-meta id="journal-meta-04778ceab05c405fbc58a5d6fe647bf8">
      <journal-id journal-id-type="nlm-ta">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="publisher-id">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.pimr.org.in/instructions.php</journal-id>
      <journal-title-group>
        <journal-title>Perspectives in Medical Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2348-229X</issn>
      <issn publication-format="print">2348-1447</issn>
    </journal-meta>
    <article-meta id="article-meta-44ead1aa3fc14f048e7c2169e84f21cb">
      <article-id pub-id-type="publisher-id">13</article-id>
      <article-id pub-id-type="doi">10.47799/pimr.1202.13</article-id>
      <article-categories>
        <subj-group>
          <subject>Case Series</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-ed4f938631074739848344b57dce1ed5">
          <bold id="strong-5724cdf637cb40e09079aacd7898d8b2">Cluster of Neurofibromatosis Cases in Remote Area of Northern Karnataka: A Case Series</bold>
        </article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name id="name-92f6f9ba7eca49bfb76c4043f62e118b">
            <surname>K Y</surname>
            <given-names>Guruprasad</given-names>
          </name>
          <xref id="x-14ff80911e5b" rid="a-ecc0e4898e44" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <name id="n-d2d9cf4c4a4b">
            <surname>Mohammed</surname>
            <given-names>Waseem Javed</given-names>
          </name>
          <email>drwj001@gmail.com</email>
          <xref id="x-1e5d169662ec" rid="a-b5342873b691" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <name id="n-6f45629a8fd4">
            <surname>R</surname>
            <given-names>Kiran Sreya</given-names>
          </name>
          <email>sreya18397@gmail.com</email>
          <xref id="x-757448e13c58" rid="a-ee1c9f91b3b8" ref-type="aff">3</xref>
        </contrib>
        <aff id="a-ecc0e4898e44">
          <institution>Professor &amp; HOD, Department of Dermatology, Faculty of Medical Sciences, KBN University, Kalaburagi, Karnataka</institution>
        </aff>
        <aff id="a-b5342873b691">
          <institution>Associate Professor, Department of Dermatology, Faculty of Medical Sciences, KBN University, Kalaburagi, Karnataka</institution>
        </aff>
        <aff id="a-ee1c9f91b3b8">
          <institution>Junior Resident, Department of Dermatology, Faculty of Medical Sciences, KBN University, Kalaburagi, Karnataka</institution>
        </aff>
      </contrib-group>
      <pub-date date-type="pub">
        <day>31</day>
        <month>8</month>
        <year>2024</year>
      </pub-date>
      <volume>12</volume>
      <issue>2</issue>
      <fpage>70</fpage>
      <lpage>74</lpage>
      <history>
        <date date-type="received">
          <day>6</day>
          <month>6</month>
          <year>2024</year>
        </date>
        <date date-type="accepted">
          <day>12</day>
          <month>8</month>
          <year>2024</year>
        </date>
        <date date-type="rev-recd">
          <day>10</day>
          <month>7</month>
          <year>2024</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>©2023 (Guruprasad K Y) et al. This is an open-access journal, and articles are distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.</copyright-statement>
        <copyright-year>2024</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-c3f270cc7a6d4ff9913d22704691cf4a">
        <title id="abstract-title-c3f270cc7a6d4ff9913d22704691cf4a">Abstract</title>
        <p id="paragraph-72962d7a93be4c78b818dd9e93d9f1ec">Tumours of the nerve system and skin are hallmarks of neurofibromatosis, a neurocutaneous condition. One class of inherited illnesses known as phakomatoses includes neurofibromatosis type 1 (NF1) or von Recklinghausen disease. It may show up anywhere in the body, including the skin, eyes, bones, and organs. We report a visually recorded seven cases of NF1 from same area. Every single patient had some kind of skin symptom. We describe the presence of several isolated neurofibromas, café au lait macules, axillary and inguinal freckling, neurological or cognitive dysfunction, and Lisch nodules in 100% of the eyes as ocular symptoms. Also, a rare occurrence of plexiform neuroma seen. Rare and familial presentation and similar cases in the same region, these findings collectively underscore the complex nature of the patient's medical presentation, necessitating a multidisciplinary approach to management and care.</p>
      </abstract>
      <kwd-group id="kwd-group-98264c74143845109507ee7031342eba">
        <title>Keywords</title>
        <kwd>Axillary freckling</kwd>
        <kwd>Lisch nodules</kwd>
        <kwd>Neuroma</kwd>
        <kwd>Neurofibromatosis (NF)</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>None</funding-statement>
      </funding-group>
    </article-meta>
  </front>
</article>
