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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="Case series">
  <front>
    <journal-meta id="journal-meta-fbdc956e2dc54220b1f2eb0483fcfe6a">
      <journal-id journal-id-type="nlm-ta">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="publisher-id">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.pimr.org.in/instructions.php</journal-id>
      <journal-title-group>
        <journal-title>Perspectives in Medical Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2348-229X</issn>
      <issn publication-format="print">2348-1447</issn>
    </journal-meta>
    <article-meta id="article-meta-4f950a1475d347c298c64f5cc2187182">
      <article-id pub-id-type="publisher-id">0016</article-id>
      <article-id pub-id-type="doi">10.47799/pimr.1001.16</article-id>
      <article-categories>
        <subj-group>
          <subject>Case Series</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-098694aec5f64677b3b0ad5ac8bf095d">Giant Bullae In Lung Parenchyma — A Case Series</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name id="name-a83128b4e7144f36aaad7ef0b000e630">
            <surname>Chenimilla</surname>
            <given-names>Nagender Prasad</given-names>
          </name>
          <email>seeprasad@gmail.com</email>
          <xref id="x-74d4779f2fac" rid="a-d80870622d2c" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <name id="name-25434b5280e24d4bb3372f43db489665">
            <surname>Krishna B</surname>
            <given-names>Ramya</given-names>
          </name>
          <xref id="x-15e1f6e5aa88" rid="a-a2213e97369d" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name id="name-16067ceae4a2478691dcfcd325108b75">
            <surname>Madire</surname>
            <given-names>Ramu</given-names>
          </name>
          <xref id="x-aad411233141" rid="a-2fdf76e31f6a" ref-type="aff">3</xref>
        </contrib>
        <aff id="a-d80870622d2c">
          <institution>Professor,Department of Pulmonology, Prathima Institute of Medial Sciences</institution>
          <addr-line>Karimnagar, Telangana</addr-line>
          <country country="IN">India</country>
        </aff>
        <aff id="a-a2213e97369d">
          <institution>Senior Resident,Department of Pulmonolgy, Prathima Institute of Medical Sciences</institution>
          <addr-line>Karimnagar, Telangana</addr-line>
        </aff>
        <aff id="a-2fdf76e31f6a">
          <institution>Associate Professor, Department of Pulmonolgy, Prathima Institute of Medical Sciences</institution>
          <addr-line>Karimnagar, Telangana</addr-line>
        </aff>
      </contrib-group>
      <pub-date date-type="pub">
        <day>30</day>
        <month>4</month>
        <year>2022</year>
      </pub-date>
      <volume>10</volume>
      <issue>1</issue>
      <fpage>84</fpage>
      <lpage>86</lpage>
      <history>
        <date date-type="received">
          <day>4</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>22</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>15</day>
          <month>1</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Perspectives in Medical Research is committed to keeping research articles Open Access. Journal permits any users to read, download, copy, print, search, or link to the full texts of these articles, or use them for any other lawful purpose, without financial, legal, or technical barriers subject to proper attribution and ownership of the rights.</copyright-statement>
        <copyright-year>2022</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-f72d97ea7ca3401999455910d501b9b8">
        <title id="abstract-title-f72d97ea7ca3401999455910d501b9b8">Abstract</title>
        <p id="paragraph-51f45f0fced34855b43648e06600ec66"><bold id="s-fd1caebe0e5d">Introduction</bold>: Bullae are air filled spaces in lung parenchyma which develop in various diseases and cause respiratory compromise. Bulla which occupies one third of hemithorax is considered as a giant bulla. </p>
        <p id="paragraph-b74a573511374ec8bd62b6cd7456fb40"><bold id="s-b902ec53078f">Case series</bold>: This case series consists of eleven cases of giant bullae with varied clinical and radiological features. Common presentations include breathlessness, associated para-septal emphysema and complications like pneumothorax. </p>
        <p id="paragraph-b42683db4152489b877f948823031781"><bold id="s-1c5200e4bf40">Conclusion</bold>: Patients presenting with acute chest symptoms should also be evaluated for bullous disease and Computed tomography of chest can differentiate pneumothorax from giant bullae. </p>
      </abstract>
      <kwd-group id="kwd-group-fef84b253b0f466a874759f67a5d55d1">
        <title>Keywords</title>
        <kwd>Giant bulla</kwd>
        <kwd>bullous emphysema</kwd>
        <kwd>Pneumothorax.</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>Nil</funding-statement>
      </funding-group>
    </article-meta>
  </front>
</article>
