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  <front>
    <journal-meta id="journal-meta-69863ba7008a47a4a22f7568b2a2ea50">
      <journal-id journal-id-type="nlm-ta">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="publisher-id">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.pimr.org.in/instructions.php</journal-id>
      <journal-title-group>
        <journal-title>Perspectives in Medical Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2348-229X</issn>
      <issn publication-format="print">2348-1447</issn>
    </journal-meta>
    <article-meta id="article-meta-ac00acdb58c94f689f2342444608b4a2">
      <article-id pub-id-type="publisher-id">0001</article-id>
      <article-id pub-id-type="doi">10.47799/pimr.1101.01</article-id>
      <article-categories>
        <subj-group>
          <subject>Original Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-d2e92595fe104fbfb1612f2af55eb25c">Laboratory derangements and clinical picture of Covid-19 in pediatric age group: A retrospective study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name id="n-063f21444759">
            <surname>Petimani</surname>
            <given-names>Mahalaxmi S</given-names>
          </name>
          <email>mahalaxmi.petimani@gmail.com</email>
          <xref id="x-2296202179a5" rid="a-352483426236" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <name id="n-f64ecc406904">
            <surname>Kotian</surname>
            <given-names>Greeshma B</given-names>
          </name>
          <xref id="x-c040106c1116" rid="a-b94ee22d94eb" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <name id="n-a67d2778ac8b">
            <surname>Adake</surname>
            <given-names>Prabhakar</given-names>
          </name>
          <email>dradake82@gmail.com</email>
          <xref id="x-9617208b92a1" rid="a-ab06ca727332" ref-type="aff">3</xref>
        </contrib>
        <aff id="a-352483426236">
          <institution>Associate Professor,Department of Biochemistry, KAHER's JGMM Medical College</institution>
          <addr-line>Hubli, Karnataka</addr-line>
        </aff>
        <aff id="a-b94ee22d94eb">
          <institution>Associate Professor,Department of Biochemistry, A.J.Institute of Medical Sciences</institution>
          <addr-line>Manglore, Karnataka</addr-line>
        </aff>
        <aff id="a-ab06ca727332">
          <institution>Professor and Head,Department of Pharmacology, KAHER's JGMM Medical College</institution>
          <addr-line>Hubli, Karnataka</addr-line>
        </aff>
      </contrib-group>
      <pub-date date-type="pub">
        <day>30</day>
        <month>4</month>
        <year>2023</year>
      </pub-date>
      <volume>11</volume>
      <issue>1</issue>
      <fpage>1</fpage>
      <lpage>5</lpage>
      <history>
        <date date-type="received">
          <day>10</day>
          <month>2</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>4</day>
          <month>3</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>15</day>
          <month>2</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Perspectives in Medical Research is committed to keeping research articles Open Access. Journal permits any users to read, download, copy, print, search, or link to the full texts of these articles, or use them for any other lawful purpose, without financial, legal, or technical barriers subject to proper attribution and ownership of the rights.</copyright-statement>
        <copyright-year>2023</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-47c284dc5c0b44b8a9f7f42f1bfcf886">
        <title id="abstract-title-47c284dc5c0b44b8a9f7f42f1bfcf886">Abstract</title>
        <p id="paragraph-c00ef245fe3645c9a8d59889f263c16b"><bold id="strong-b2361be464614cfd84c701a7417d6a98">Aim:</bold> To assess the clinical presentation and laboratory derangements of pediatric covid-19 patients admitted to the tertiary care hospital.</p>
        <p id="paragraph-7b5f7d43253049e591ec91c0294ed2b3"><bold id="strong-120986f5fe8f4ec69a8b74ac945b93ac">Methodology:</bold> The present retrospective study was started after the approval of the Institutional Ethics Committee. Clinical (Sp02, final diagnosis and outcome) and biochemical parameters (Complete Blood Count, Liver Function Test, Renal Function Test, Lactate De-Hydrogenase, D-dimer, C-Reactive Protein, and Serum ferritin) of pediatric covid-19 patients were collected from Central Laboratory and Medical Record Department of our institution. Patient names were anonymized and data were analyzed. The results are expressed in percentages.</p>
        <p id="paragraph-9736b6c4003a4e368050f6aee8cbc63d"><bold id="strong-6f016916de5540a5b7f4dc2f352e1c3e">Results:</bold> A total of 16 pediatric covid-19 patient details were identified and collected who were admitted during our study period. Out of 16 patients, 09 (56.2%) were female and the remaining 07 (43.7%) were male. Out of 16, 05 patients had mild covid, 07 were moderate and the remaining 04 suffered from severe covid-19 infection. The mean values of oxygen saturation, LDH, D-dimer, CRP, and Ferritin were 88%, 249.4U/L, 1140.9 ng/ml, 16.17 mg/dl, and 61.7 µg/L respectively. Mean values of 17.9 mg/dl and 0.4 mg/dl were recorded for blood urea and S.creatinine. Regarding liver function tests, mean values of 1.7mg/dl, 0.2mg/dl, 1.5mg/dl, 82.4 U/L, 55 U/L, 135.6 U/L respectively noted for total bilirubin, direct, indirect, SGOT, SGPT and ALP. Regarding patient outcomes, all the patients were covered and discharged from the hospital. </p>
        <p id="paragraph-092012519ef343e08510fffb20068399"><bold id="strong-ad7755eb471946688e6b1ea0bae0a923">Conclusion:</bold> The present study has found an increase in laboratory mean values of liver function tests but the mean values of C-Reactive protein, LDH, and d-dimer which are the acute inflammatory markers are highly disrupted compared to normal ranges. </p>
      </abstract>
      <kwd-group id="kwd-group-3b9b720319db47a98f24d1c3c8bea067">
        <title>Keywords</title>
        <kwd>COVID­19</kwd>
        <kwd>Laboratory parameters</kwd>
        <kwd>Pediatric</kwd>
        <kwd>Retrospective studies</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>Nil</funding-statement>
      </funding-group>
    </article-meta>
  </front>
</article>
