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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="Original Article">
  <front>
    <journal-meta id="journal-meta-20d2b4de9c144300814eaa6ecc968ff0">
      <journal-id journal-id-type="nlm-ta">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="publisher-id">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.pimr.org.in/instructions.php</journal-id>
      <journal-title-group>
        <journal-title>Perspectives in Medical Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2348-229X</issn>
      <issn publication-format="print">2348-1447</issn>
    </journal-meta>
    <article-meta id="article-meta-1b5326486e5d43539e285c9baeeefa2d">
      <article-id pub-id-type="publisher-id">0004</article-id>
      <article-id pub-id-type="doi">10.47799/pimr.1002.04</article-id>
      <article-categories>
        <subj-group>
          <subject>Original Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-90c905bc50694c328525d67f5b282d82">Intracranial Magnetic Resonance Venography of Superior Sagittal Sinus, Straight Sinus and Cerebral Venous Channels: Normal Anatomy and Variations in North Indian Population</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name id="n-40000cafc499">
            <surname>Agarwal</surname>
            <given-names>Nitin</given-names>
          </name>
          <email>esicdc111@gmail.com</email>
          <xref id="x-f071e0d930d0" rid="a-a6feaece76be" ref-type="aff">1</xref>
        </contrib>
        <contrib contrib-type="author" corresp="yes">
          <name id="n-a401cf9b4120">
            <surname>Pakhiddey</surname>
            <given-names>Rohini</given-names>
          </name>
          <email>rohiniddey@gmail.com</email>
          <xref id="x-4f3365e175c7" rid="a-ba5a1765f1d1" ref-type="aff">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name id="n-ff0f11a1873f">
            <surname>Dhissa</surname>
            <given-names>Neel Chand</given-names>
          </name>
          <degrees>MBBS,MS</degrees>
          <email>neeldhissa@gmail.com</email>
          <xref id="x-9ebb352859aa" rid="a-ba5a1765f1d1" ref-type="aff">2</xref>
        </contrib>
        <aff id="a-a6feaece76be">
          <institution>Assistant Profeesor,Department of Anatomy, G.S Medical College</institution>
          <addr-line>Hapur, Uttar Pradesh</addr-line>
          <country country="IN">India</country>
        </aff>
        <aff id="a-ba5a1765f1d1">
          <institution>Associate Profeesor,Department of Anatomy, ESIC Dental College &amp; Hospital</institution>
          <addr-line>Delhi, Delhi, 110089, 9899988287</addr-line>
          <country country="IN">India</country>
        </aff>
      </contrib-group>
      <pub-date date-type="pub">
        <day>30</day>
        <month>8</month>
        <year>2022</year>
      </pub-date>
      <volume>10</volume>
      <issue>2</issue>
      <fpage>13</fpage>
      <lpage>20</lpage>
      <history>
        <date date-type="received">
          <day>2</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>26</day>
          <month>2</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>21</day>
          <month>2</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Perspectives in Medical Research is committed to keeping research articles Open Access. Journal permits any users to read, download, copy, print, search, or link to the full texts of these articles, or use them for any other lawful purpose, without financial, legal, or technical barriers subject to proper attribution and ownership of the rights.</copyright-statement>
        <copyright-year>2022</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-b2cd128358b0471b99c4d9cba97618c6">
        <title id="abstract-title-b2cd128358b0471b99c4d9cba97618c6">Abstract</title>
        <p id="paragraph-5fcfdf5097c4415d856d1cded4055163">The intracranial dural venous sinuses can be injured leading to thrombosis with in the dural sinuses causing headache, abnormal vision, weakness of the face and limbs on one side of the body, and seizures.Magnetic Resonance Venography (MRV) is one of the preferred methods of evaluation of the cerebral venous sinus anatomy, variations and pathology, particularly in the diagnosis<sup id="superscript-2f0c1aabc11342aa874194e3bed4bf5f"> </sup>of venous sinus thrombosis. </p>
        <p id="paragraph-abb428e5c31241f78717143ec684c238">The purpose of this study is to evaluate the use of MRV to depict the normal intracranial venous anatomy and its variants in North Indian population which can help to avoid potential pitfalls in the diagnosis of dural venous sinus thrombosis, venous infarcts and venous hemorrhage. </p>
        <p id="paragraph-8497bf9ab85245b599468489b7fd8d68"><bold id="strong-fadf866e936043bb8b32bbc8292b47a3">Aim:</bold>The purpose of this study is to evaluate the use of MRV to depict the normal intracranial venous anatomy and its variants in North Indian population, which can help to avoid potential pitfalls in the diagnosis of dural venous sinus thrombosis, venous infarcts and venous hemorrhage. </p>
        <p id="paragraph-c0134e96b6534092a5b3fc0acc8fc8c0"><bold id="strong-b61fb7b62dc144f0a45c8aaee51c1fc2">Materials:</bold>The present study was undertaken in the Departments of Anatomy and Radiodiagnosis at a North Indian tertiary care teaching hospital over a period of two years. Magnetic Resonance Venograms (MRV) of patients attending the radiology department were used to study the normal anatomy and variations in the dural venous sinuses. 50 MRV scans of which 26 were of females and 24 of male, were included in the study. Anatomical variations and variations in drainage of the dural venous sinuses were assessed and statistical analysis was done.</p>
        <p id="paragraph-8456dc9a145145638edc522c8dd196c7"><bold id="strong-1234b10df14f40f4b3d6b4b5c19ae9cd">Results:</bold>For both superior sagittal sinus drainage and straight sinus drainage, the proportion of veins draining in right and left transverse sinuses and confluence of sinuses was significantly different in the two age groups (p&lt;0.001) in both males and females. Partial splitting of superior sagittal sinus in anterior one third or posterior one third was also seen. Statistically significant findings were observed regarding the laterality for vein of Labbe &amp; vein of Trolard.</p>
        <p id="paragraph-f845010649084e039c1d3785eda17f7a"><bold id="strong-5b976f0c7bd94a57bf3161d6d4c152c5">Conclusion:</bold>MR venography is an excellent diagnostic technique to visualise anatomy and anatomic variations of venous sinuses as observed in our study. The partial splitting of superior sagittal sinus in either anterior one third or posterior one third as seen in our study, can cause misdiagnosis of thrombosis. Hence, knowledge of normal anatomy and anatomic variations in the intracranial venous sinuses is very important to diagnose cerebral venous sinus thrombosis accurately. </p>
      </abstract>
      <kwd-group id="kwd-group-e72fa92b086a42cea62b644f267a76e4">
        <title>Keywords</title>
        <kwd>Anatomical Variations</kwd>
        <kwd>Cerebral Venous Thrombosis</kwd>
        <kwd>Dural Venous Sinus</kwd>
        <kwd>Headache</kwd>
        <kwd>Magnetic Resonance Venography</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>Nil</funding-statement>
      </funding-group>
    </article-meta>
  </front>
</article>
