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<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="Original Article">
  <front>
    <journal-meta id="journal-meta-78454d5a735a454dbd0d0cf90585c710">
      <journal-id journal-id-type="nlm-ta">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="publisher-id">Prathima Institute of Medical Sciences</journal-id>
      <journal-id journal-id-type="journal_submission_guidelines">https://www.pimr.org.in/instructions.php</journal-id>
      <journal-title-group>
        <journal-title>Perspectives in Medical Research</journal-title>
      </journal-title-group>
      <issn publication-format="electronic">2348-229X</issn>
      <issn publication-format="print">2348-1447</issn>
    </journal-meta>
    <article-meta id="article-meta-62412493dc4d4c92a41f8cf83917b50c">
      <article-id pub-id-type="publisher-id">6</article-id>
      <article-id pub-id-type="doi">10.47799/pimr.0903.06</article-id>
      <article-categories>
        <subj-group>
          <subject>original Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title id="article-title-dae1245105e34e3dac65d178a5717159">
          <bold id="strong-731c60cff94e474ea74234a7a3c931c1">A Study </bold>
          <bold id="strong-59297fefab9a4df4a5372fe17989317b">of Management of Primary Chalazion in Adults by Intralesional Injection of</bold>
          <bold id="strong-ab3c3ae53794427e9ed375145d1dad93"> </bold>
          <bold id="strong-a5c34c14992b42ed8c294c66ceb692af">Triamcinolone Acetonide</bold>
        </article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name id="name-60ba630433ad443bab0850d0518e59e9">
            <surname>Akbani</surname>
            <given-names>Idris</given-names>
          </name>
          <email>mohdidrisakbani@yahoo.com</email>
          <xref id="xref-0053406f18934da496a1286e52133f8c" rid="aff-c9292bc3e36c40cd840c1dce50bdef42" ref-type="aff">1</xref>
        </contrib>
        <aff id="aff-c9292bc3e36c40cd840c1dce50bdef42">
          <institution>Department of Ophthalmology, Rajiv Gandhi Institute of Medical Sciences</institution>
          <addr-line>Adilabad, Telangana</addr-line>
        </aff>
      </contrib-group>
      <pub-date date-type="pub">
        <day>6</day>
        <month>1</month>
        <year>2022</year>
      </pub-date>
      <volume>9</volume>
      <issue>3</issue>
      <fpage>22</fpage>
      <lpage>25</lpage>
      <history>
        <date date-type="received">
          <day>6</day>
          <month>3</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>14</day>
          <month>6</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>6</day>
          <month>5</month>
          <year>2021</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Perspectives in Medical Research is committed to keeping research articles Open Access. Journal permits any users to read, download, copy, print, search, or link to the full texts of these articles, or use them for any other lawful purpose, without financial, legal, or technical barriers subject to proper attribution and ownership of the rights.</copyright-statement>
        <copyright-year>2021</copyright-year>
      </permissions>
      <abstract id="abstract-abstract-title-0b15ea917207449b9a0dfb4b4ecea884">
        <title id="abstract-title-0b15ea917207449b9a0dfb4b4ecea884">Abstract</title>
        <p id="paragraph-4dc3db31f0ab4d839c5899244b85ae35">
          <bold id="s-d9b515a5cdc1">Introduction</bold>
        </p>
        <p id="p-dc368a2e6b9e">A chalazion is a common non-effective granuloma of the meibomian glands of eyelids. They are commonly found on the tarsal conjunctival surface and the eyelid margins. It may be ignored by the patients until it reaches a considerable size. Recently the use of intralesional corticosteroids has shown promising results. We in the present study tried to evaluate the outcomes of intralesional triamcinolone acetonide injection in the management of Chalazion.</p>
        <p id="paragraph-23e2160354bc4b9b8029a46f583a3949">
          <bold id="strong-5688db3b288a496fbb2d52b1c497c1b2">Methods</bold>
        </p>
        <p id="paragraph-1c39f4e17c034ce39fd94124dfc9ed60">The current study was carried on Patients with chalazion attending Ophthalmology OPD of Rajiv Gandhi Institute of Medical Sciences, [RIMS], Adilabad. Successive patients with small multiple marginal chalazia were included. Patients were selected based on the amenability of treatment with intralesional triamcinolone acetonide injections. </p>
        <p id="paragraph-3e93ead5eddb4282b3d9b28b93cd1360">A chalazion is a common non-infective granuloma of the meibomian glands of eyelids. They are commonly found on the tarsal conjunctival surface and the eyelid margins. It may be ignored by the patients until it reaches a considerable size. Recently the use of intralesional corticosteroids has shown promising results. We in the present study tried to evaluate the outcomes of intralesional triamcinolone acetonide injection in the management of Chalazion.</p>
        <p id="paragraph-22ff1d26595d4c4aaea2bd06927d10d8">
          <bold id="strong-6f99867abeda4bdfa09a42e96f8700ae">Results</bold>
        </p>
        <p id="paragraph-324a0b26beb94289b17353986772dad7">Group I with very small-sized chalazia&lt; 5 mm out of n=22 included in Group I resolution after one week following treatment was found in 72.72%. Resolution following repeated injection after one week was found in 18.18%. In group II (chalazia size 5-7 mm) out of n=28 cases, 46.24% resolved after first injection and 39.28% cases resolved after the second injection and no resolution was found in 14.28% cases after one month.</p>
        <p id="paragraph-6f89f3c22adc4dfeac0e848079b1ee76">
          <bold id="strong-d613792e276f496599c5c612adf9cdf5">Conclusion</bold>
        </p>
        <p id="paragraph-e79838632cb147a9929642a7fcc53aa4">Patients with small chalazia who are not amenable to incision and curettage intralesional triamcinolone acetonide injection appear to be a better option. Intralesional triamcinolone acetonide injections were found to be effective in resolving acute and sub-acute chalazia of soft to firm consistency irrespective of their duration.</p>
      </abstract>
      <kwd-group id="kwd-group-5c817fdc304744b69212f43422c10d06">
        <title>Keywords</title>
        <kwd>Chalazia</kwd>
        <kwd>conjunctiva</kwd>
        <kwd>Triamcinolone Acetonide Injection</kwd>
        <kwd>Subcutaneous</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>Nil</funding-statement>
      </funding-group>
    </article-meta>
  </front>
</article>
