Panduranga Rao Sanagapati¹, Panduranga Rao Sanagapati², Mahesh Kumar Kandukuri³, Shanthi Bonagiri⁴

¹Assistant Professor, Department of Transfusion medicine, Nizam's Institute of Medical Sciences, Hyderabad, India, ²Professor and Head, Department of Transfusion medicine, Nizam's Institute of Medical Sciences,Hyderabad, India, ³Assistant Professor, Department of Pathology, MallaReddy Institue of Medical Sciences, Hyderabad, India, ⁴Associate professor, Department of Transfusion medicine, Nizam's Institute of Medical Sciences, Hyderabad, India.

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Introduction: Chronic neutrophilic leukemia (CNL) is a rare BCR/ABL negative myeloproliferative disease characterized by persistent mature neutrophilia, raised serum vitamin B12, raised neutrophil alkaline phosphatase (NAP), hepatosplenomegaly, and raised serum uric acid. We report a very rare case of CNL who initially responded to treatment and finally developed respiratory tract infection and septicemia and succumbed to death.

Keywords :Leukemia, Myeloproliferative disease Neutrophilia