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Case Report - Abstract

Chronic neutrophilic leukemia: A very rare case report

Year : January - April 2015 2015 | Volume : 3 | Issue : 1 Page : 31 -336

Panduranga Rao Sanagapati1, Panduranga Rao Sanagapati2, Mahesh Kumar Kandukuri3, Shanthi Bonagiri4

1Assistant Professor, Department of Transfusion medicine, Nizam's Institute of Medical Sciences, Hyderabad, India, 2Professor and Head, Department of Transfusion medicine, Nizam's Institute of Medical Sciences,Hyderabad, India, 3Assistant Professor, Department of Pathology, MallaReddy Institue of Medical Sciences, Hyderabad, India, 4Associate professor, Department of Transfusion medicine, Nizam's Institute of Medical Sciences, Hyderabad, India.

Address for correspondence: Dr. Sudhir Kumar Vujhini, Plot no-292, Lakshmisai Meadows, Road Number 6,Beeramguda, Ramachandrapuram, Medak, Telangana, India.

Email: vujhini07@yahoo.com

Abstract

Introduction: Chronic neutrophilic leukemia (CNL) is a rare BCR/ABL negative myeloproliferative disease characterized by persistent mature neutrophilia, raised serum vitamin B12, raised neutrophil alkaline phosphatase (NAP), hepatosplenomegaly, and raised serum uric acid. We report a very rare case of CNL who initially responded to treatment and finally developed respiratory tract infection and septicemia and succumbed to death.

Keywords :Leukemia, Myeloproliferative disease Neutrophilia

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