Volume: 1 Issue: 1
Year: 2013, Page: 29-31,
During routine dissection of cadavers for 1st MBBS students in 2009-2010 a normal built adult male cadaver presented with a hypertrophied right kidney and an atrophied left kidney. In the right kidney (16cmx6.5cmx4.5cm) the capsule was difficult to strip off. The cut section showed well demarcated cortex and medulla. Blood clots were present in renal sinuses. Histopathology showed glomerulosclerosis, thyroid casts in atrophic tubules thickening and hyalinization of blood vessels, inflammatory changes in the interstitium. The left kidney (4cmx2.5cmx1cm) showed thinned outcortex on cut section. Calyces were not well distinguished. Capsule was adherent to its surface. Glomerulosclerosis and predominant atrophic changes in the tubules observed in histopathology. Vascular compromise secondary to hypertension caused ischaemic changes in the left kidney. This superimposed with chronic renal infection had resulted into an atrophic left kidney which led to a compensatory hypertrophy of the right kidney.
Keywords: Hypertrophied kidney, atrophic kidney,renal failure, hypertension, renal infection
1) Healy J C. Kidney. In , Standring S (ed). Gray's Anatomy, 39th edition , Edinburgh , Elsevier Churchill Livingstone, 2005; 1269- 1277
2) Dutta A K. The Urinary System . In Dutta A K(ed). Essentials of Human Anatomy, Part I, 8th edition, Kolkata, Current Books International, 2009; 289
3) Mohan H . The Kidney and lower Urinary Tract. In Mohan H (ed) Text book of Pathology , 6th edition, New Delhi ,Jaypee Brothers, 2010; 653- 666
4) Laszik ZG, Silva F G. Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura and other Thrombolic Microangiopathies. In, Jennette C J(ed) . Heptinstall's th Pathology of the Kidney, 6th edition Philadelphia, PA 19106 USA, Lippincott Williams & Wilkins, 2007; 732-733
5) Nadasdy T, Silva F G. Adult Renal Disease. In, Carter D (ed) Sternberg's Diagnostic Surgical Pathology, 4th edition, Philadelphia PA 19106 USA, Lippincott Willams & Wilkins, 2004; 1927
6) Alpers C E. The Kidney, In Kumar V(ed). Robbins and Cotran Pathologic Basis of Disease , 8th edition, New Delhi , Elsevier publication , 2012 ; 950-51
7) Olson Jean L. Renal disease caused by hypertension. In Jennet C J(ed) Heptinstall's Pathology of the Kidney,6th edition Vol 2, Philadelphia, PA 19106 USA, Lippincott Willams & Wilkins, 2007; 944-947
8) Sommers SC, Relman A S, Smithwick RH . Histologic studies of kidney biopsy specimens from patient of hypertension. Am J Pathol 1958; 34:685-715
9) Michie AJ, Michie CR, Ragni MC. Kidney function in unilatetral pyelonephritis II, Physiologic interpretation . The Am J of Med 1957; 2:22.
10) Dossetor R S. Renal compensatory hypertrophy in adults. Br J Radiol 1975; 48: 993-95
11) Bengtsson C, Hood B. The unilateral small kidney with special reference to hypoplastic kidney . Int J of uro and neph 1971; 3: 337-51
Dutta R,Phukon MJ, G Anandam. Unilateral hypertrophied right kidney and contralateral atrophy of left kidney: In a setting of malignant hypertension – A case report. Perspectives in medical research 2013; 1: 29-31