Volume: 2 Issue: 1
Year: 2014, Page: 28-32,
Introduction: Acute poisoning is an important cause of morbidity and mortality in India. It is estimated that more than 50,000 people die every year from toxin exposure. In India, intentional cases alone reach some 126,000 cases annually and organophosphorus compounds constitute major poisonings.
Materials and Methods: A cross sectional, descriptive study was conducted among 30 cases of acute poisoning admitted in Prathima Institute of Medical Sciences, Karimnagar, Andhra Pradesh during September 2011-12. Socio-demographic variables assessed were age, sex and area wise distribution of the respondents. Type of poison, the amount ingested, clinical presentation and outcome were studied.
Results: In this study, maximum cases 13 (43.4%) were between 17 to 20 years, males 17 (57%) were more commonly involved in acute poisoning and 20 (67%) cases came from rural areas. The majority 13 (43.3%) of cases were organophosphates poisonings and 28 (93%) of cases were of suicidal intentions. Most of the suicidal poisonings were due to economical problems 14 (50%), followed by broken relationships 6 (21%) and studies related reasons were observed in 5 (18%) of cases. Out of total 30 cases of poisonings in this study, 26 cases (86.66%) were recovered completely, whereas 4 cases (13.3%) expired.
Conclusion: Prevention of poisoning requires further exploration of underlying factors in their cultural context and effective strategies including management of these problems. Changing the knowledge, attitudes and behaviors of the community and improvement in the medical treatment plan is required to curtail the incidence and mortality.
Keywords: Acute poisoning, Organophosphorus compounds, India
1. Pillay VV. Modern Medical Toxicology. 4thedition. New Delhi: Jaypee Brothers Medical Publishers; 2013.
2. Sharma BR, Harish D, Sharma V, Vij K. Poisoning in Northern India: Changing trends, causes and prevention thereof. Med Sci Law 2002; 42(3):251- 7.
3. Khajja BS ,Sharma M, Singh R , Girish K. Mathur G K. Forensic Study of Indian Toxicological Plants as Botanical Weapon (BW): AReview. J Environment Analytic Toxicol 2011; 1:4.
4. Gunnell D, Eddleston M. Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries. Int J Epidemiol. 2003 Dec;32(6):902-9.
5. G Ravi, C Ra j endir an, P Thiruma l a i kolundusubramanian, N Babu. Poison control, training and research center, Institute of Internal Medicine, Government General Hospital, Madras Medical College, Chennai, India. Presented at the 6th Annual congress of Asia Pacific Association of Medical Toxicology, Bangkok, Thailand 2-14 December 2007.
6. Kumar SV1, Venkateswarlu B, Sasikala M, Kumar GV. A study on poisoning cases in a tertiary care hospital. J Nat Sci Biol Med. 2010 Jul;1(1):35-9.
7. Multani AS, Bal BS, Singh SP, Singh TP, Salwan S, Shivcharan. Spectrum of Acute Poisoning in Medical Emergencies - A Proscpective Study. JAPI 2003; 51:1199-1200.
8. Bansal N, Uniyal N, Kashyap P V, Varma A. A profile of poisoning in Uttarakhand. Transworld Medical Journal. 1(4):128-130.
9. Vaidya YP, Hulke SM. Study of trends of poisoning in the cases reported to government hospital, Yavatmal. Chron Young Sci 2012;3:63-7.
Devi S, Dasari A, Dasyam SK, Sai Shripada Rao K. A study of the clinical profile of 30 consecutive cases of poisoning presenting to a rural tertiary care center. Perspectives in medical research 2014; 2: 28-32