Volume: 10 Issue: 3
Year: 2022, Page: 87-92, Doi: https://doi.org/10.47799/pimr.1003.16
Received: Jan. 31, 2022 Accepted: April 19, 2022 Published: April 19, 2022
Background: Acute respiratory illness with fever and respiratory symptoms such as cough and shortness of breath comprise the main clinical presentations of Corona virus disease (COVID-19).Clinical manifestations in COVID-19 shows significant regional variations.
Objective of the study: To study the demographic and clinical profiles of laboratory confirmed COVID-19 patients in South India
Methods: In this cross sectional study,patients diagnosed with COVID-19 by reverse transcriptase-polymerase chain reaction (RT-PCR) test were taken up for the study.History of fever,throatpain,cough,breathlessness,malaise were taken.Blood pressure,respiratory rate,oxygen saturation were recorded.Data on co-morbid illnessness like diabetes,hypertension,renal disease were also noted .All these were correlated to assess the clinical course of COVID-19
Results: Of the total 518 patients,257(49.6%) patients were in the age group of 46 to 65 years and 309 (59.7 %) patients were males. History of fever was present in 349(67.38%) patients and cough was present in 291 (56.17%) patients. Throat pain and running nose was present in 291 (56.2%)and 110 (21.23%) patients respectively. Heart rate was between 60 and 100 beats per minute in 472 (80.3%) of patients and 102 (19.7%) patients had respiratory distress with respiratory rate ≥24. Oxygen saturation was between 90-93% in 57 (9.85%) patients and 87(16.8%) patients were on oxygen support with 21(4.1%) patients on non-invasive ventilation. A total of 291(56.2%) patients were treated with steroids. Diabetes mellitus was present in 214(41.3%), hypertension in 150 (29%) patients. Case fatality rate was 2.1%
Conclusion: Severe disease and lower oxygen saturation was associated with older age and co-morbid diseases particularly diabetes
Keywords: COVID-19, clinical profile, RT-PCR, fever, diabetes, oxygen saturation
Zhu, N, Zhang, D & Wang, W . 2019. A Novel Coronavirus from Patients with Pneumonia in China. N Engl J Med 382(8):727–733.
Ahmad, S, Kumar, P, Shekhar, S, Saha, R, Ranjan, A, Pandey, S & Epidemiological, . 2021. Clinical, and Laboratory Predictors of In-Hospital Mortality Among COVID-19 Patients Admitted in a Tertiary COVID Dedicated Hospital, Northern India: A Retrospective Observational Study. J Prim Care Community Health 12:481–486.
Jamil, M, Bhattacharya, P K & Barman, B . 2021. Clinical and Demographic Profile of COVID-19 Patients: A Tertiary Level Hospital-Based Study From Northeast India. Cureus 13(10):18881.
Mowla, S G, Azad, K A, Kabir, A, Biswas, S, Islam, M R, Banik, G, Khan, M M, Rohan, K & &alam, M A . 2020. Clinical Profile of 100 Confirmed COVID-19 Patients Admitted in Dhaka Medical College Hospital. Journal of Bangladesh College of Physicians and Surgeons 38:29–36.
Bhandari, S, Bhargava, A, Sharma, S, Keshwani, P, Sharma, R & Banerjee, S . 2020. Clinical Profile of Covid-19 Infected Patients Admitted in a Tertiary Care Hospital in North India. J Assoc Physicians India 68(5):32610859.
Mishra, V, Burma, A D, Das, S K, Parivallalmb, , Amudhan, S & Rao, G N . 2020. COVID-19-Hospitalized Patients in Karnataka:Survival and Stay Characteristics. Indian J Public Health 64:221–225.
Hasan, M Z, Biswas, N K & Aziz, A M . 2021. Clinical profile and short-term outcomes of RT-PCR- positive patients with COVID-19: a cross-sectional study in a tertiary care hospital in. BMJ Open 11:55126.
Li, L-Q, Huang, T & Wang, Y-Q . 2020. COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 92:577–83.
Nasir, N, Habib, K & Khanum, I . 2021. Clinical characteristics and outcomes of COVID-19: experience at a major tertiary care center in Pakistan. J Infect Dev Ctries 15:480–489.
Soni, S L, Kajal, K, Yaddanapudi, L N & Malhotra, P . 2021. Demographic & clinical profile of patients with COVID-19 at a tertiary care hospital in north India. Indian J Med Res 153(1-2):115–125.
Rajiva, Muruganantham M, Mukherjee, G, Singh, Pmp, Saxena, A, Chary, S & Mahar, S S . 2021. Clinico-epidemiological profile of COVID-19 cases: Our experiences. J Med Sci Res 9(3):155–161.
Lee, Yonghyun, Min, Pokkee, Lee, Seonggu & Kim, Shin-Woo . 2020. Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients. Infectious Diseases, Microbiology & Parasitology.Journal of Korean Medical Science 35(18):174.
Ye, Q, Wang, B & Mao, J . 2020. The pathogenesis and treatment of the `Cytokine Storm' in COVID-19. The Journal of Infection 80:607–613.
Elavarasi, A . 2022. Clinical features, demography, and predictors of outcomes of SARS-CoV-2 infection at a tertiary care hospital in India: A cohort study. Lung India 39(1):16–26.
Joshi, Shashank, Parkar, Jalil & Ansari, Abdul . 2021. Agam Vora,etal.Role of favipiravir in the treatment of COVID-19. International Journal of Infectious Diseases 102:501–508.
Green, Ilan, Merzon, Eugene, Vinker, Shlomo, Golan-Cohen, Avivit & Magen, Eli . 2021. COVID-19 Susceptibility in Bronchial Asthma. The Journal of Allergy and Clinical Immunology: In Practice 9(2):684–692.
Ramya N, Shanu JEJ, Prabhu Shankar S. Clinical and demographic profile of COVID19 patients- A cross-sectional study from a tertiary care medical college hospital from South India. Perspectives in Medical Research. 2022;10(3):87-92 DOI: 10.47799/pimr.1003.16