Perspectives in Medical Research

Volume: 6 Issue: 3

  • Open Access
  • Original Article

Cytological and histopathological correlation of Soft tissue tumors

P Hemalatha1,Saritha2,Padmavathi3, Sandhya Anil4

1,2Assistant Professor,3Associate Professor,4Professor & Head, Department of Pathology,Kakatiya Medical College,Warangal,Telangana,India.
Address for correspondence: Dr P Hemalatha, Assistant Professor, Department of Pathology,Kakatiya Medical College,Warangal,Telangana,India
Email: [email protected]

Year: 2018, Page: 40-44,

Abstract

Introduction: Fine needle aspiration cytology (FNAC) is useful in distinguishing accurately between benign and malignant soft tissue tumors and subclassify them into general and clinically relavant cases to initiate treatment.It's accuracy when applied by experienced and well trained practitioner matches that of histopatholgy in providing equivocal diagnosis.
Materials and Methods :This 2yrs retrospective and prospective study was done in Mahatma Gandhi Memorial Hospital Warangal by considering both exclusion and inclusion criteria in 240 cases. History & clinical evaluation were done.They were subjected to FNAC and later biopsy done and correlated.
Results :FNAC revealed diagnostic material in 233 cases and7 cases were inconclusive for diagnosis.220 cases (92%) diagnosed as benign and 13cases(5.4%) were diagnosed as malignant on FNAC.Out of which 216(98%) benign cases were correlated on histopathology as benign,4 cases were diagnosed as malignant on HPE.All the13(100%) cases diagnosed as malignant on FNAC were correlated with histopathology as malignant.Out of the 7 inconclusive cases 4 cases diagnosed as benign and 3 cases diagnosed as malignant on histopathology. Diagnostic accuracy of benign cases is 97% & malignant cases is 100%.
Conclusion :FNAC is very useful procedure in preoperative diagnosis of benign&malignancy of soft tissue tumors with certain limitations.It is safe useful procedure of low financial cost, low morbidity with compliance& acceptable diagnostic accuracy.

Keywords: Fine needle aspiration cytology, soft tissue tumors, Histopathological examination.

References

1 Shaham Beg,ShaistaM Vasenwala,Nazima Haider. A comparison of cytological and histopathological findings and role of immunostains in the diagnosis of soft tissue tumors J Cyto 2012; 29(2):125-130.
2 Parajuli S,Lakhey M . efficacy of fine needle aspiration cytology in diagnosing soft tissue tumours. Journal of Pathology of Nepal (2012);99: 305-308.
3. Bezabih M. Cytological diagnosis of soft tissue tumors.Pathology 2007; 28: 368-76.
4. Dey P,MallikMK ,Gupta SK, Vashishta R K. Role of fine needle cytology in the diagnosis of soft tissue tumors and tumor like lesions. Diagn Cytopathol 1996;15:23-32.
5. Nagira K ,Yamamoto T, AkisueT, MarutiT ,Hitora T,et al. Reliability of fine needle aspiration biopsy in the inital diagnosis of tissue lesions.Diag Cytopathol 2002;27;354- 61.
6. Bennert KW, Abdul Karim FW. Fine needle aspiration vs.core needle biopsy of soft tissue tumors.A comparison.Acta Cytol 1994;38:381-499.
7. Layfield LJ,Anders KH, Glasgow BJ,Mira JM. Fine needle aspiration of primary soft-tissue tumors.Arch Pathol Lab.Med 1986;110;420-4.
8. Rekhi B,Gorad BD,KakadeAC,Chinoy R. Scope of FNAC in the diagnsis of soft tissue tumors a study from tertiary cancer referral centre in India.CytoJornal 2007;4;20.
9. Kilpatrick SE,Gsinger KR. Soft tissue sarcoma; The utility and limitation of fine needle aspiration biopsy.Am J Clin Pathol 1998;110;50-68.
10. Wakely PE,Kniesel JS.Soft tissue aspiration cytopatholgy.Cancer 2000;90:292-8.
11. Akerman M,Rydholm A,Persson BM. Aspiration cytology of soft tissue tumors.The 10 yrs experience at an orthopedic oncologycentre.Cytopathology 2007;18:243- 40.
12. Kulkarni DR,Hemant R,Kkandaker et al.Fine needle aspiration cytology of soft tissue tumors in correlation with histopathology.Indian J pathol,Microbiol 2002;3: 45- 8.
13. Amin MS,Luqman M.Fine needle aspiration biopsy of soft tissue tumors.J coll Physicians Surg Pak 2003;13;625-8.

Cite this article

Hemalatha P,Saritha,Padmavathi, Sandhya A. Cytological and histopathological correlation of Soft tissue tumors. Perspectives in Medical Research 2018; 6(3):40-44.

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