Volume: 4 Issue: 3
Year: 2016, Page: 8-11,
Background: There exists a synergistic relation between reproductive tract infection (RTI) and HIV infection, both of which are associated with women of reproductive age group
Aims & Objectives: The present study was undertaken to determine RTI burden by eliciting socio demographic profiles, past gynaecological history, obstetric history, and laboratory based prevalence of total RTI/ STI and HIV infection in reproductive age group women and treatment seeking behaviour.
Materials and Methods :260 patients with reproductive age group of 15-50 years with chief complaint of vaginal discharge were examined for reproductive tract infection by collecting vaginal, high vaginal, endocervical swabs. 5ml of blood collected, serum separated and tested for HIV using WHO strategy, as per national guidelines of NACO.
Results: Syphilis was the most common RTI identified in 38.3% cases followed by Chlamydiasis in 30.7% of cases followed by Gardnerella vaginalis infection (bacterial vaginosis) constituting 18.1%, Candida albicans 13.3%, finally Trichomoniasis 7.6% of cases noted. HIV seropositivity was 24.6%.
Conclusion: Prevalence of RTIs is high in women of reproductive age group making them vulnerable to acquisition of HIV infection. Early etiological diagnosis using simple conventional techniques is helpful in instituting specific treatment for complete cure of RTIs in prevention of HIV transmission.
Keywords: Reproductive tract infection, syphilis, HIV, Prevalence
1. Training module on the surveillance of Sexually Transmitted Diseases. National AIDS Control Organization, Ministry of Health and Family Welfare Government of India. P.13.
2. World Health Organisation. A new approach to STD control and AIDS prevention. Global News 1994; 4: 13- 15.
3. Wasserheit JN, Aral SO. The dynamic topology of sexually transmitted disease epidemics: implications for prevention strategies. Journal of Infectious Diseases 1996; 174(Suppl. 2): S201-213.
4. Ray K, et al. Changing pattern of sexually transmitted diseases at a STD Centre. Indian Journal of Medical Research 2006; 124: 559-568.
5. Khanna N. Sexually transmitted diseases in India. Indian Journal of Sexually Transmitted Diseases 2002; 232: 58- 66.
6. Murgesh SB, Sugareddy, Raghunath S. Pattern of sexually transmitted diseases at Davangere. Indian Journal of Sexually Transmitted Diseases 2004; 25: 9-12.
7. Chatterjee M, Ramadasan P. Profile of sexually transmitted diseases in and around Jabalpur, MP. Indian Journal of Sexually Transmitted Diseases 2004; 25: 13-17.
8. Centres for Disease Control and Prevention. Incorporating HIV prevention into the medical care of persons living with HIV. Recommendations of CDC, the Health Resources and Services Administration, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. Morb Mortal Wkly Rep. 2003;52 (RR-12):1-24.
9. Collee JG, Fraser AG, Marmion BP, Simmons A. Mackie and Mc Cartney Practical Medical Microbiology, 14th Ed. Churchill Livingstone, London, 1999:699-793-812.
10. Genbase AC, Rowley JT, Mertens TE. Global Epidemiology of sexually transmitted diseases. Lancet 1998; 352 (suppl.III) : 2-4.
11. Hawkes S, Morison L, Foster S, et al. reproductive tract infections in women in low income, low prevalence situations: assessment of syndromic management in Matlab, Bangladesh. The Lancet 1999;354:1776-1781.
12. Aggarwal AK, Kumar R, Gupta V, et al. Community based study of reproductive tract infections among ever married women of reproductive age in a rural area of Haryana, india. J Commun Dis 1999; 31(4) :223-228.
13. Latha K, Senapati SK, Sridhar S, et al. Prevalence of clinically detectable gynaecological morbidity in India: Result of four community based studies. The Journal of Family Welfare 1997; 41(4) 8-16.
14. Murthy NS. Reproductive Health Status of Indian Women: A Scenario, Obs and Gynae Today 2002; 7(8): 432-440.
15. Tumwesigye E, 1994, Telling signs and symptoms, Afrc. Womenhealth 2(3): 31-7.
16. CU-Uvins S, Hogern JW, Warren D et.al. 1994, Prevalence of lower genital tract lesions among human HIV seropositive and High-risk HIV seronegative women. HIV epidemiology Research Study group, Clin. Infect.1999 Nov. 29; (5) :1145-50.
17. Eduardo Calore E, Jose Cavaliere M, Kasumi Shirata N, Aranio MF. Papillomavirus in cervicovaginal smears of women infected with human immunodeficiency virus, rev. Poull Med. 1995; Nov. Dec 113(6): 1009-11.
18. Moodley P, Wilkonson D, Connolly C, MoodleyJ, Sturm AW. Trichomonas vaginalis is associated with pelvic inflammatory disease in women infected with human immunodeficiency virus, Clin infect Dis. 2002 Feb 15; 34(4): 519-22. Epub 2002 Jan 07.
19. Panja S. Sexually transmitted diseases Part-II, Gynaecology for post graduates and practitioners, ed. Bijoy Sree Sen Gupta et. al. Pub. B.I. Churchill Living Stone Pvt. Ltd. Ed. I, 1998 CH. 35, P.406.
20. Wang CC, McCleland RS, Reilly M et. al. The effect of treatment of vaginal infection shedding of human immunodeficiency virus type I: 6: J. Infect. Dis. 2001; Apr. ;183(7):1017-22.
21. Buksi EA, Cohen CR, Stevens CE et. al. Effects of HIV-I infection on microbial origin of pelvic inflammatory disease and on efficacy of ambulatory oral therapy. Am. J. Obstet. “Gynaecol 1999 Dec ;181(6): 1374-81.
22. Cohen CR, Plummer FA, Mugo N, Maclean I, Shec Bukusi EA, Irungu E, Sinis, Bwayo J, Brunham RC. Increased interleukin 10 in the endocervical secretions of women with non ulcerative sexually transmitted diseases: a mechanism for enhanced HIV-I transmission, AIDS, 1999 Feb.25; 13(3) : 327-32.
23. Kamya MR, Nsubugua P. Grant RM, Hellman N, 1995. The high prevalence of genital herpes among patient with genital ulcer disease in Uganda, 32: Sex transm. Dis. 1995 Nov-Dec; 22(6): 351-4.
24. KlugmanKP, patel J, Sischy A, Mc Intyre JA., Serological markers of sexually transmitted diseases associated with HIV-I infection in pregnant black women, S, Afr, Med. J. 1991 Sept.7; 80(5): 243-4.
25. Wiesenfeld HC, Hiller SL, Krohn M.A. et. al. Lower genital tract infection and endometritis insight on to subclinical Pelvic inflammatory disease. Obst. Gynecol. 2002 Sep: 100(3) 456-63.
Sreedevi S, Jyothi K, Seetha Mahalakshmi B. HIV seropositivity in reproductive tract infections in women attending MGM Hospital, Warangal.Perspectives in medical research 2016; 4(3):8-11.