Volume: 5 Issue: 2
Year: 2017, Page: 20-24,
Introduction: Anemia is a common medical disorder affecting a lot of women in pregnancy in the developing countries. The occurrence of anaemia in pregnant women is attributed mainly to malnutrition. Anaemia might become fatal as to contribute to maternal mortality & morbidity. Hence present study is under taken to know the role of oral therapy in both anaemic & non anaemic pregnant women.
Materials and Methods : The study was conducted at antenatal OPD between October 2005 to July 2006.Ninety pregnant women were selected & divided into 2 groups.44 normal pregnant women (control group) were compared with 46 pregnant women with anaemia(study group) aged between 20-30 years.
Haematological parameters were analysed by SYSMEX auto analyser. In current study we compared haematological responses to oral iron therapy(Zincofer) in both control & study groups. Student ‘t’ test was used for comparison between study and control groups.
Results :The change in RBC count between the two groups was insignificant over the pregnancy period. A significant increase in Hb%,MCH & MCHC has been observed in anaemic pregnant women over the trimesters with oral iron therapy which is an indicative of increased iron absorption .
Conclusion :The study will be indicative about the rational use of iron in iron deficiency anemia. Daily oral iron supplementation is strongly recommended during pregnancy to reduce the prevalence of anemia.
Keywords: Anemia,Pregnancy,Oral iron.
1. Ministry of Health and Family Welfare, Government of India. Guidelines for control of Iron deficiency anaemia. New Delhi: Ministry of Health and Family Welfare, Government of India; 2013.
2. Brabin L, Nicholas S, Gogate A, Karende A. High prevalence of anemia among women in Mumbai, India. Food Nutr Bull 1998;19:205-9.
3. Sarin AR. Severe anemia of pregnancy, recent experience. Int J Gynecol Obstet 1995 ;50( suppl): S45-9.
4. LozoffB, Jimenez E, Vlolf A Vl. Long-term developmental outcome of infants with iron deficiency. N Engl J Med 1992;325:687-94.
5. Viteri FE. The consequences of iron deficiency and anemia in pregnancy. Adv Exp Med Biol 1994;352: 127-39.
6. Prema K, Neela KS, Ramalakshmi BA. Anemia and adverse obstetric outcome. Nutr Rep Int 1981;23:637-43.
7. Centers for disease control.CDC Criteria for anaemia in children and child bearing aged women.MMWR 1989;38:400-4.
8. Institute of medicine, Committee on Nutritional status during pregnancy and lactation.Nutrition during pregnancy.Washington,DC: National Academy press 1990;272-98.
9. Centers for disease Control ,Criteria for anemia in children and childbearing aged women .MMWR 1989;38:400-4
10. Singh K, Fong YF, Kuperan P. A comparison between intravenous iron polymaltose complex (Ferrum Hausmann) and oral ferrous fumarate in the treatment of iron deficiency anemia in pregnancy. Eur J HaematoI1998;60: 119-24.
11. Kennedy E. Dietary reference intakes :development and uses for assessment of micronutrient status of women–a global prospective Am J Clin Nutr 2005 ;81(suppl):1194S7S.
12. Sharma JB, Soni D, NIurthy NS, Malhotra M. Effect of dietary habits on prevalence of anemia in pregnant women of Delhi. J Obstet Gynaecol Res 2003;29:73-8.
13. Sharma JB. Medical complications in pregnancy. In: Sharma JB, eds. The obstetric protocol. 1st ed. Delhi, India: Jaypee Brothers, 1998:78-98.
14. S.K.Sood,R.Ramachandaniran,Rani et al. WHO sponsored collaborative studies on nutritional anaemia in India.The effect of parenteral iron administration in the control of anaemia of pregnancy.Br J Nutr 1979; 42:399-406.
15. Sharma J.B. Nutritional anemia during pregnancy in non industrial countries, Progress in Obst.& Gynae (Studd)2003, vol -15,103-122.)
16. Sharma JB, Arora BS , Kumar S Goel S, Dhamija A. Helminth and protozoal intestinal infection an important cause for anemia in pregnant women in Delhi, India , J Obstet Gynecol Ind200:51(6):58-61.
17. Review of Indian clinical research with ferrous ascorbate .In Allahabadia Shroff,Agarwals 2006, Feb /MarIssue Pg - 15(Eds). Fogs 1Times 2006,Fab/Mar Issue P-15.
Padmaja T, Srinivas Ch, Bhagya Lakshmi K. Role of oral Iron therapy in anemic and non anemic pregnant women.Perspectives in Medical Research 2017;5(2):20-24.