Volume: 12 Issue: 1
Year: 2024, Page: 49-51, Doi: https://doi.org/10.47799/pimr.1201.10
Received: July 12, 2024 Accepted: March 30, 2024 Published: April 10, 2025
Synovial chondromatosis is a rare cartilaginous neoplasm that most commonly affects the knee joint. Histologically, it presents as a multinodular cartilaginous proliferation showing clusters of chondrocytes. These can be quite atypical, simulating chondrosarcoma. The lesion is usually self-limited but sometimes may exhibit a more aggressive clinical course characterized by multiple local recurrences. Chondrosarcomatous transformation in synovial chondromatosis is exceedingly rare but has been documented.
Until recently, synovial chondromatosis was considered a reactive process. Recent cytogenetic studies have shown recurrent chromosomal abnormalities, especially involving chromosome6, therefore supporting a clonal, neoplastic nature of this intriguing lesion.
Keywords: Reactive process, Chromosome 6, Ambrose Pare, Knee
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©2024 (Diksha Molugu Lingamurthy) et al. This is an open-access journal, and arƟcles are distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
Lingamurthy DM, CH SL, Arasi T. Synovial Chondromatosis of Right Knee: A Case Report. Perspectives in Medical Research. 2024;12(1):49-51 DOI: 10.47799/pimr.1201.10